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A Multi-Center, Randomized, Third Party blinded Study to evaluate the Safety and Efficacy of Topical application of Nitrogen Mustard 0.02% in a propylene glycol ointment (PG) vs. Nitrogen Mustard 0.02% in an Aquaphor ointment (AP) in patients with Stage I or IIA Mycosis Fungoides.

Description: The purpose of this study is to determine the safety and effectiveness of topical Nitrogen Mustard for the treatment of Stage I and Stage IIA Mycosis Fungoides. The study may last up to 27 months and will require 16 study visits. Subjects will receive $50 for every study visit completed. Please feel free to call our office at (617) 726-5066 Monday through Friday between 9:00 am and 5:00 pm for more information.

Eligibility Criteria: Subjects must have a diagnosis of stage I or IIA (cutaneous only) Mycosis Fungoides. He/she must have tried other topical treatments like steroids or phototherapy, but must stop all treatments before being enrolled. If female, you cannot be pregnant or breastfeeding. Other restrictions will be explained at the screening visit.

Institution: Brigham and Women's Hospital

Principal Investigator: Alexandra B. Kimball, MD, MPH

Enrollment Information: For further information please contact Lynne Hermosilla at (617) 726-5066 or e-mail harvardskinstudies@partners.org.

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Date Created: 3/13/2007 6:56:36 AM
Date Last Modified: 3/17/2008 1:24:02 PM
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Contact Information:
  Clinical Unit for
Research Trials in Skin
617-726-5066
harvardskinstudies@partners.org